Compounds

7-OH, pseudo, MGM-15, MIT-A, mitragynine, cat’s claw, and the federal scheduling action.

• The Federal 7-OH Ban: Dates, Scope, What It Means

  DEA has filed notice to place 7-OH above a threshold, pseudo, MGM-15, and MGM-16 in Schedule I. The dates, the legal process, the public comment window, and what to do if you're still using.

• Kratom Leaf & Mitragynine

  Kratom basics, what mitragynine does in the body, how it relates to 7-OH, and why concentrated 7-OH products are not the same thing as leaf.

• 7-OH (7-Hydroxymitragynine)

  Concentrated 7-hydroxymitragynine, how it differs from kratom leaf, why dependence builds fast, and what makes it taperable.

• MGM-15

  MGM-15 (dihydro-7-hydroxymitragynine), the long-acting reduced 7-OH. The same compound sold under the labels MIT-A and (mislabeled) DHM. Chemistry, the COA-testing problem, regulatory landscape, taper plan, Suboxone induction notes.

• MGM-16

  The fluorinated analog of MGM-15, a 2014 medicinal-chemistry compound named in scheduling proceedings but not documented in any US consumer product to date.

• MIT-A and DHM

  Products marketed as MIT-A or DHM contain MGM-15. The full picture lives on the MGM-15 page; this page is a pointer.

• 7-Pseudoindoxyl / MP (Mitragynine Pseudoindoxyl)

  Mitragynine pseudoindoxyl (MP), receptor affinity, why bupe induction is harder, what to watch for.

• Cat’s Claw

  Products marketed as 'Cat's Claw' or 'Rhynchophylline' at smoke shops and gas stations are being built around corynoxine B, an opioid-active alkaloid that dodges the 7-OH scheduling. What's really in them.